degron
 n.— «Mutations in these sequences (or “degrons” as they are called) prevent Gli1 degradation, causing, rather, the Gli1 protein to accumulate, and lead to accelerated tumorigenesis. Mutations in these sequences (or “degrons” as they are called) prevent Gli1 degradation, causing, rather, the Gli1 protein to accumulate, and lead to accelerated tumorigenesis.» —“Stopping the clock: Genetics of tumor latency in skin cancer” in Cold Spring Harbor Laboratory EurekaAlert Jan. 19, 2006. (source: Double-Tongued Dictionary)

Tagged with →